O75027 | ABCB7_HUMAN

The ABCB7-ABCB7 homodimer is located in the inner mitochondrial membrane. It exports glutathione-coordinated iron-sulfur clusters from the mitochondria to the cytosol.

UniProt Entry

UniProt:
O75027
Start - end:
1 - 752
Sequence length:
752
Sequence MD5 checksum:

Structures

Category, format, type:
AB-INITIO, MMCIF, ATOMIC
Created:
2021-11-04
Method, confidence:
THEORETICAL MODEL, pLDDT = 85.92
AlphaFold2 Initial release tuned for multimer prediction ([github/hegelab/betafold](https://github.com/hegelab/betafold-initialrelease)) were used for the prediction. The `--full_dbs` option, which runs with all genetic databases used at CASP14, was set. Database versions were the same as in this AF2 release, except UniClust30, for which we used the 2021_06 release, since `hhblits` produced error for some sequences when using `uniclust30_2018_08`. The `--max_template_date` argument was set into the future to utilize all available experimental structures as potential templates. The structure top ranked based on pLDDT score were selected and presented as a PDB formatted file (its name ends with full.pdb). Low complexity regions were visually inspected and removed if concluded non-sense (e.g. traversing membrane region) and presented as the main cif and pdb files.
UniProt start - end, coverage:
105 - 715, 81%
Oligomeric state (chains):
HOMODIMER ()
Literature:
To be published.
Cif file:
hege-abc-0012.cif
PDB file:
hege-abc-0012.pdb
Full predicted pdb file:
hege-abc-0012.full.pdb
All structure files:
hege-abc-0012.zip