P45844 | ABCG1_HUMAN

The ABCG1-ABCG1 homodimer plays an important role in cholesterol homeostasis. It exports cholesterol to high density lipoprotein (HDL).

UniProt Entry

UniProt:
P45844
Start - end:
1 - 678
Sequence length:
678
Sequence MD5 checksum:

Structures

Category, format, type:
AB-INITIO, MMCIF, ATOMIC
Created:
2021-11-08
Method, confidence:
THEORETICAL MODEL, pLDDT = 80.10
AlphaFold2 Initial release tuned for multimer prediction ([github/hegelab/betafold](https://github.com/hegelab/betafold-initialrelease)) were used for the prediction. The `--full_dbs` option, which runs with all genetic databases used at CASP14, was set. Database versions were the same as in this AF2 release, except UniClust30, for which we used the 2021_06 release, since `hhblits` produced error for some sequences when using `uniclust30_2018_08`. The `--max_template_date` argument was set into the future to utilize all available experimental structures as potential templates. The structure top ranked based on pLDDT score were selected and presented as a PDB formatted file (its name ends with full.pdb). Low complexity regions were visually inspected and removed if concluded non-sense (e.g. traversing membrane region) and presented as the main cif and pdb files.
UniProt start - end, coverage:
20 - 678, 97%
Oligomeric state (chains):
HOMODIMER ()
Literature:
To be published.
Cif file:
hege-abc-0004.cif
PDB file:
hege-abc-0004.pdb
Full predicted pdb file:
hege-abc-0004.full.pdb
All structure files:
hege-abc-0004.zip