Q9H221 | ABCG8_HUMAN

The ABCG5-ABCG8 heterodimer maintains the cellular cholesterol levels. These proteins mediate secretion of sterols into bile and the gut lumen.

UniProt Entry

UniProt:
Q9H221
Start - end:
1 - 673
Sequence length:
673
Sequence MD5 checksum:

Structures

Category, format, type:
AB-INITIO, MMCIF, ATOMIC
Created:
2021-10-29
Method, confidence:
THEORETICAL MODEL, pLDDT = 77.35
AlphaFold2 Initial release tuned for multimer prediction ([github/hegelab/betafold](https://github.com/hegelab/betafold-initialrelease)) were used for the prediction. The `--full_dbs` option, which runs with all genetic databases used at CASP14, was set. Database versions were the same as in this AF2 release, except UniClust30, for which we used the 2021_06 release, since `hhblits` produced error for some sequences when using `uniclust30_2018_08`. The `--max_template_date` argument was set into the future to utilize all available experimental structures as potential templates.The structure top ranked based on pLDDT score were selected and presented as cif and pdb files.
UniProt start - end, coverage:
1 - 673, 100%
Oligomeric state (chains):
HETERODIMER ()
Literature:
To be published.
Cif file:
hege-abc-0001.cif
PDB file:
hege-abc-0001.pdb
All structure files:
hege-abc-0001.zip